Article
Combined haplotype analysis of the interleukin-19 and -20 genes: relationship to plaque-type psoriasis.
Genes and immunity - 1 Dec 2004
Kõks S, Kingo K, Rätsep R, Karelson M, Silm H, Vasar E
Abstract excerpt
There is increasing evidence to suggest that the newly discovered cytokines interleukin (IL)-19 and -20 have a role in the function of epidermis and in psoriasis. The genes encoding these cytokines locate into the genomic IL-10 region on human chromosome 1. The aim of the present study was to analyze whether single-nucleotide polymorphisms (SNPs) in these genes have an impact on the susceptibility for psoriasis....
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