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Article

IL-19, IL-20 and IL-24: potential therapeutic targets for autoimmune diseases

12 Nov 2010

Abstract excerpt

IL-19, IL-20 and IL-24 are members of the IL-10 family of cytokines, the human IL-19, IL-20 and IL-24 genes are all located on the q32 region of chromosome 1, and the three cytokines also share a common receptor IL-20R1/IL-20R2 heterodimer. These cytokines due to the similarity and shared receptor usage, are quite overlapping in function. Recently, the available evidence has indicated that interaction of these...

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PMID: 21073280
DOI: 10.1517/14728222.2011.534461

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