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IL-20 receptor cytokines in autoimmune diseases

7 Sept 2018

Abstract excerpt

IL-19, IL-20, and IL-24 are the members of IL-10 family. They are also known as IL-20 receptor (IL-20R) cytokines as they all signal through the IL-20RA/IL-20RB receptor complex; IL-20 and IL-24 (but not IL-19) also signal through the IL-20RB/IL22RA1 receptor complex. Despite their protein structure homology and shared use of receptor complexes, they display distinct biological functions in immune regulation,...

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PMID: 30260500
DOI: 10.1002/jlb.mr1117-471r

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