Article
Polymorphisms in the interleukin-20 gene: relationships to plaque-type psoriasis.
Genes and immunity - 1 Mar 2004
Kingo K, Kõks S, Nikopensius T, Silm H, Vasar E
Abstract excerpt
We analyzed the frequency of single-nucleotide polymorphisms (SNPs) at positions -1053 (rs 2981572), 1380 (rs 2981573), 1462 (rs 2232360), and 3978 (rs 1518108) of the human interleukin-20 (IL-20) gene by tetraprimer ARMS-PCR method. A significant association between patients with psoriasis and the G allele at position -1053 (P<0.05) was established. The pairwise linkage disequilibrium (LD) matrix showed that the...
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