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Article

The anti-sigma factor TcdC modulates hypervirulence in an epidemic BI/NAP1/027 clinical isolate of Clostridium difficile.

PLoS pathogens - 1 Oct 2011

Carter Glen P, Douce Gillian R, Govind Revathi, Howarth Pauline M, Mackin Kate E, Spencer Janice, Buckley Anthony M, Antunes Ana, Kotsanas Despina, Jenkin Grant A, Dupuy Bruno, Rood Julian I, Lyras Dena

Abstract excerpt

Nosocomial infections are increasingly being recognised as a major patient safety issue. The modern hospital environment and associated health care practices have provided a niche for the rapid evolution of microbial pathogens that are well adapted to surviving and proliferating in this setting, after which they can infect susceptible patients. This is clearly the case for bacterial pathogens such as Methicillin...

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Identifiers

PMID: 22022270
DOI: 10.1371/journal.ppat.1002317
PMCID: PMC3192846

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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