Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Heparan sulfate proteoglycans regulate autophagy in Drosophila.

Autophagy - 3 Aug 2017

Reynolds-Peterson Claire E, Zhao Na, Xu Jie, Serman Taryn M, Xu Jielin, Selleck Scott B

Abstract excerpt

Heparan sulfate-modified proteoglycans (HSPGs) are important regulators of signaling and molecular recognition at the cell surface and in the extracellular space. Disruption of HSPG core proteins, HS-synthesis, or HS-degradation can have profound effects on growth, patterning, and cell survival. The Drosophila neuromuscular junction provides a tractable model for understanding the activities of HSPGs at a synapse...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagosomes
Share to Autophagy
Share to Autophagy-Related Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fat Body

Share to Heparan Sulfate Proteoglycans

Share to Muscles

Share to Neuromuscular Junction

Share to Synapses

Source

Open in PubMed Open full text

Identifiers

PMID: 28402693
DOI: 10.1080/15548627.2017.1304867
PMCID: PMC5584867

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Heparan sulfate proteoglycans regulate autophagy in Drosophila.PMID 28402693Read ↗

Cell type-specific requirements for heparan sulfate biosynthesis at the Drosophila neuromuscular junction: effects on synapse function, membrane trafficking, and mitochondrial localization.Semantic proximity Read ↗

Heparan Sulfate Structure Affects Autophagy, Lifespan, Responses to Oxidative Stress, and Cell Degeneration in Drosophila parkin Mutants.Semantic proximity Read ↗

Neuronal-specific impairment of heparan sulfate degradation in Drosophila reveals pathogenic mechanisms for Mucopolysaccharidosis type IIIA.Semantic proximity Read ↗

Misregulation of the Ubiquitin–Proteasome System and Autophagy in Muscular Dystrophies Associated with the Dystrophin–Glycoprotein ComplexSemantic proximity Read ↗

A genetic screen in Drosophila reveals novel cytoprotective functions of the autophagy-lysosome pathway.Semantic proximity Read ↗

Dynamic regulation of inter-organelle communication by ubiquitylation controls skeletal muscle development and disease onsetSemantic proximity Read ↗

Identification of secretory autophagy as a mechanism modulating activity-induced synaptic remodelingSemantic proximity Read ↗

Endogenous chondroitin extends lifespan by inhibiting VHA-7-mediated tubular lysosome formation.Semantic proximity Read ↗

Genetic analysis of the Drosophila ESCRT-III complex protein, VPS24, reveals a novel function in lysosome homeostasis.Semantic proximity Read ↗

Heparan sulfate modified proteins affect cellular processes central to neurodegeneration and modulate <i>presenilin</i> functionSemantic proximity Read ↗

Perlecan regulates bidirectional Wnt signaling at the Drosophila neuromuscular junction.Semantic proximity Read ↗

Signaling through the Dystrophin Glycoprotein Complex affects the stress-dependent transcriptome in DrosophilaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.