Article
CGHsweep: an algorithm for analyzing chromosomal aberrations in genome using aCGH profiles.
In silico biology - 1 Jan 2007
Karmaker Amitava, Kwek Stephen
Abstract excerpt
DNA copy number aberrations along the genome are vital markers for studying pathogenesis of various diseases including cancers. Array-based Comparative Genome Hybridization (aCGH), which is a high-throughput cytogenetic method, helps in identifying genome-wide copy number aberrations, both gains and losses. Here, we propose a computational technique to analyze aCGH data and to identify potential DNA copy number...
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