Article
Array-Based Comparative Genomic Hybridization (aCGH).
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017
Zhang Chengsheng, Cerveira Eliza, Romanovitch Mallory, Zhu Qihui
Abstract excerpt
Copy number variations (CNVs) in the genomes have been suggested to play important roles in human evolution, genetic diversity, and disease susceptibility. A number of assays have been developed for the detection of CNVs, including fluorescent in situ hybridization (FISH), array-based comparative genomic hybridization (aCGH), PCR-based assays, and next-generation sequencing (NGS). In this chapter, we describe a...
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