Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Persistent infection with Pseudomonas aeruginosa in ventilator-associated pneumonia.

American journal of respiratory and critical care medicine - 1 Sept 2008

El Solh Ali A, Akinnusi Morohunfolu E, Wiener-Kronish Jeanine P, Lynch Susan V, Pineda Lilibeth A, Szarpa Kristie

Abstract excerpt

RATIONALE: Pseudomonas aeruginosa is one of the leading causes of gram-negative ventilator-associated pneumonia (VAP) associated with a mortality rate of 34 to 68%. Recent evidence suggests that P. aeruginosa in patients with VAP may persist in the alveolar space despite adequate antimicrobial therapy. We hypothesized that failure to eradicate P. aeruginosa from the lung is linked to type III secretory system...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Bacterial Agents
Share to Bacterial Toxins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Bronchoalveolar Lavage Fluid

Share to Drug Resistance, Bacterial

Share to Neutrophils

Share to Pseudomonas aeruginosa

Share to Pseudomonas Infections

Share to Recurrence

Source

Open in PubMed Open full text

Identifiers

PMID: 18467510
DOI: 10.1164/rccm.200802-239OC
PMCID: PMC2542430

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Persistent infection with Pseudomonas aeruginosa in ventilator-associated pneumonia.PMID 18467510Read ↗

Type III protein secretion is associated with poor clinical outcomes in patients with ventilator-associated pneumonia caused by Pseudomonas aeruginosa.Semantic proximity Read ↗

Type III protein secretion is associated with death in lower respiratory and systemic Pseudomonas aeruginosa infections.Semantic proximity Read ↗

The Pseudomonas aeruginosa type III secretion system has an exotoxin S/T/Y independent pathogenic role during acute lung infection.Semantic proximity Read ↗

Alveolar Response toPseudomonas aeruginosa: Role of the Type III Secretion SystemSemantic proximity Read ↗

Type II secretion system of Pseudomonas aeruginosa: in vivo evidence of a significant role in death due to lung infection.Semantic proximity Read ↗

Diversity of virulence phenotypes among type III secretion negative Pseudomonas aeruginosa clinical isolates.Semantic proximity Read ↗

Pseudomonas aeruginosa-induced apoptosis is defective in respiratory epithelial cells expressing mutant cystic fibrosis transmembrane conductance regulator.Semantic proximity Read ↗

Porphyromonas gingivalis modulates Pseudomonas aeruginosa-induced apoptosis of respiratory epithelial cells through the STAT3 signaling pathway.Semantic proximity Read ↗

Activities of Pseudomonas aeruginosa effectors secreted by the Type III secretion system in vitro and during infection.Semantic proximity Read ↗

Cell Death of Human Polymorphonuclear Neutrophils Induced by a Pseudomonas aeruginosa Cystic Fibrosis Isolate Requires a Functional Type III Secretion SystemSemantic proximity Read ↗

ExoU expression by Pseudomonas aeruginosa correlates with acute cytotoxicity and epithelial injury.Semantic proximity Read ↗

Pyocyanin production by Pseudomonas aeruginosa induces neutrophil apoptosis and impairs neutrophil-mediated host defenses in vivo.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.