Article
Type III protein secretion is associated with poor clinical outcomes in patients with ventilator-associated pneumonia caused by Pseudomonas aeruginosa.
Critical care medicine - 1 Mar 2002
Hauser Alan R, Cobb Enesha, Bodi Maria, Mariscal Dolors, Vallés Jordi, Engel Joanne N, Rello Jordi
Abstract excerpt
OBJECTIVE: Pseudomonas aeruginosa is a frequent cause of ventilator-associated pneumonia. Recent evidence suggests that production of type III secretion proteins is correlated with increased pathogenicity in both cellular and animal models of infection. The objective of this study was to determine whether this system contributes to disease severity in humans with ventilator-associated pneumonia. DESIGN:...
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