Article
Diversity of virulence phenotypes among type III secretion negative Pseudomonas aeruginosa clinical isolates.
PloS one - 1 Jan 2014
Toska Jonida, Sun Yan, Carbonell Dalina Alvarez, Foster Altreisha N-S, Jacobs Michael R, Pearlman Eric, Rietsch Arne
Abstract excerpt
Pseudomonas aeruginosa is a frequent cause of acute infections. The primary virulence factor that has been linked to clinical disease is the type III secretion system, a molecular syringe that delivers effector proteins directly into host cells. Despite the importance of type III secretion in dictating clinical outcomes and promoting disease in animal models of infections, clinical isolates often do not express...
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