Article
Clock-dependent and independent transcriptional control of the two isoforms from the mouse Rorgamma gene.
Genes to cells : devoted to molecular & cellular mechanisms - 1 Dec 2008
Mongrain Valérie, Ruan Xuan, Dardente Hugues, Fortier Erin E, Cermakian Nicolas
Abstract excerpt
Accumulating evidence indicate that molecular mechanisms generating circadian rhythms display some degree of tissue-specificity. More specifically, distinct patterns of expression for nuclear receptors of the ROR family indicate that the transcriptional control of the clock gene Bmal1 differs among tissues. This study aims to investigate the expression of Rorgammaisoforms (Rorgamma and Rorgammat) and characterize...
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