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Article

Increased lipid oxidation heralds diabetes onset in DR.lyp/lyp rats.

Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association - 1 Aug 2008

Akesson L, Gelling R W, Jensen R, Ogimoto K, Fuller J M, Pefley R, Manavi S, Lernmark A, Schwartz M W

Abstract excerpt

AIM: The BB rat model of type 1 diabetes exhibits altered body weight gain and body temperature regulation prior to hyperglycemia onset, implying the existence of as yet unidentified biomarkers of autoimmune processes that destroy pancreatic beta cells. To investigate this hypothesis, we compared the metabolic profile of diabetes-resistant DR.lyp/+ rats and their diabetes-prone, congenic DR.lyp/lyp littermates in...

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PMID: 18465680
DOI: 10.1055/s-2008-1062713

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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