Article
Interleukin-1 beta gene polymorphism and traditional constitution in obese women.
The International journal of neuroscience - 1 Jun 2008
Lee Jeong-Hoon, Kwon Young-Dal, Hong Seung-Heon, Jeong Hyun-Ja, Kim Hyung-Min, Um Jae-Young
Abstract excerpt
In adipose tissue metabolism, cytokines were major regulators. mRNA expression studies show that adipocytes can synthesize both tumor necrosis factor-alpha and several interleukins (ILs), notably IL-1 beta (IL-1beta) and IL-6. In particular, IL-1beta expression is under strong genetic control. We examined the relationship among obesity, polymorphism of the IL-1beta at position +3953 in exon 5, and Sasang...
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