Article
Interleukin-1 receptor antagonist gene polymorphism and traditional classification in obese women.
The International journal of neuroscience - 1 Jan 2006
Um Jae-Young, Kim Hyung-Min, Mun Sung-Won, Song Yung-Sun, Hong Seung-Heon
Abstract excerpt
Cytokines appear to be the major regulators of adipose tissue metabolism. Interleukin- 1 receptor antagonist (IL-1ra) serum levels are increased in human obesity, and are under strong genetic control. The hypothesis was tested that the IL-1ra gene might be a candidate for obesity. Furthermore, the relationship was investigated between Sasang constitution and IL-1ra polymorphism. The frequency of a penta-allelic...
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