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Article

Association between interleukin-1 beta polymorphism (+3953) and obesity.

Molecular and cellular endocrinology - 15 Jan 2010

Manica-Cattani M F, Bittencourt L, Rocha M I U, Algarve T D, Bodanese L C, Rech R, Machado M M, Santos G F F, Gottlieb M G V, Schwanke C H A, Piccoli J E C, Duarte M F F, Cruz I B M

Abstract excerpt

It now appears that obesity is associated with a low-grade inflammation of white adipose tissue resulting from chronic activation of the innate immune system as interleukin-1 beta (IL-1). Previous investigations have described a positive association between IL-1 beta +3953 (C>T) gene polymorphism (rs 1143634) and obesity, suggesting functional effects on fat mass, fat metabolism and body mass. However, it is...

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PMID: 19666082
DOI: 10.1016/j.mce.2009.07.029

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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