Article
Association of interleukin-18 gene polymorphism with body mass index in women.
Reproductive biology and endocrinology : RB&E - 24 Apr 2012
Kim Hye-Lin, Cho Sung One, Kim Seon-Young, Kim Sung-Hoon, Chung Won-Seok, Chung Seok-Hee, Kim Sung-Soo, Ko Seong-Gyu, Jeong Chang-Hyun, Kim Su-Jin, Hong Seung-Heon, Um Jae-Young
Abstract excerpt
BACKGROUND: Interleukin (IL)-18 is an important regulator of innate and acquired immune responses and has multiple roles in chronic inflammation and autoimmune disorders. Obesity is characterized by low- grade chronic inflammation. IL-18 has been suggested as an adipogenic cytokine that is associated with excess adiposity. The purpose of this study is to evaluate the relationship between IL-18 gene polymorphisms...
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