Article

PWAS Hub: Exploring Gene-Based Associations of Common Complex Diseases

2024-01-22

Abstract excerpt

PWAS (Proteome-Wide Association Study) is an innovative genetic association approach that complements widely-used methods like GWAS (Genome-Wide Association Study). The PWAS platform involves consecutive phases. Initially, machine learning modeling and probabilistic considerations quantified the impact of genetic variants on protein-coding genes’ biochemical functions. Secondly, aggregating the variants per gene f...

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Literature Corpus work: e2775bc9-daeb-59e8-88b0-96be5ab48e00
DOI: 10.1101/2024.01.20.23300645

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