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Article

Preliminary characterization of murine cytomegaloviruses with insertional and deletional mutations in the M34 open reading frame.

Journal of medical virology - 1 Jul 2008

Baluchova Katarina, Kirby Melissa, Ahasan Mohammad M, Sweet Clive

Abstract excerpt

A viable virus could not be recovered from a mutant murine cytomegalovirus (MCMV) BAC in which the M34 ORF had been deleted (BACDeltaM34). In contrast, an M34 mutant virus (RcM34), in which the M34 ORF was interrupted by transposon insertion at nt 44,827 of the Smith MCMV BAC, was attenuated in replication both in tissue culture and in SCID mice. Similarly, mutant virus Rc3'DeltaM34, in which the 3'-end was...

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Identifiers

PMID: 18461610
DOI: 10.1002/jmv.21211

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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