Article
Isolation and characterization of a transposon-induced cytotoxin-deficient mutant of Pseudomonas aeruginosa.
Infection and immunity - 1 Feb 1991
Bopp L H, Baltch A L, Hammer M C, Franke M A, Smith R P, Lutz F
Abstract excerpt
In order to provide a better system for investigating the role of cytotoxin in pathogenesis, we mutated wild-type Pseudomonas aeruginosa PA158 by introducing a transposon. The resulting pool of mutants was screened for cytotoxin-deficient strains. One mutant strain, PA114F5, was compared with PA158. Except for cytotoxin production and antibiotic resistance (specified by the transposon), the two strains appear...
Topics
- Cytotoxins
- DNA Transposable Elements
- Drug Resistance, Microbial
- Kanamycin
- Mutation
- Pseudomonas aeruginosa