Article
Role of a cytotoxic enterotoxin in Aeromonas-mediated infections: development of transposon and isogenic mutants.
Infection and immunity - 1 Aug 1998
Xu X J, Ferguson M R, Popov V L, Houston C W, Peterson J W, Chopra A K
Abstract excerpt
Transposon and marker exchange mutagenesis were used to evaluate the role of Aeromonas cytotoxic enterotoxin (Act) in the pathogenesis of diarrheal diseases and deep wound infections. The transposon mutants were generated by random insertion of Tn5-751 in the chromosomal DNA of a diarrheal isolat...
Topics
- Aeromonas hydrophila
- Animals
- Bacterial Proteins
- Blotting, Southern
- CHO Cells
- Chromosomes, Bacterial
- Cricetinae
- Crossing Over, Genetic
- DNA Transposable Elements
- DNA, Bacterial
- Disease Models, Animal
- Enterotoxins
