Article
The truA gene of Pseudomonas aeruginosa is required for the expression of type III secretory genes.
Microbiology (Reading, England) - 1 Mar 2004
Ahn Kyung-Seop, Ha Unhwan, Jia Jinghua, Wu Donghai, Jin Shouguang
Abstract excerpt
Invasive strains of Pseudomonas aeruginosa can cause rapid host cell apoptosis by injecting the type III effector molecule ExoS. A transposon insertional mutant bank of P. aeruginosa was screened to identify P. aeruginosa genes that contribute to the ability of the bacteria to trigger host cell apoptosis. Several isolated mutants had disruptions in the fimV gene. A fimV mutant was unable to induce the expression...
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