Article
Isolation and characterization of a Pseudomonas aeruginosa gene, ptxR, which positively regulates exotoxin A production.
Molecular microbiology - 1 Jul 1996
Hamood A N, Colmer J A, Ochsner U A, Vasil M L
Abstract excerpt
Exotoxin A production in Pseudomonas aeruginosa is a complicated and highly regulated process that involves several genes. In this report, we describe the isolation of a new toxA regulatory gene (ptxR) which affects exotoxin A production in P. aeruginosa. In an iron-deficient medium, the presence...
Topics
- ADP Ribose Transferases
- Amino Acid Sequence
- Bacterial Proteins
- Bacterial Toxins
- Chromosomes, Bacterial
- Cloning, Molecular
- DNA, Bacterial
- Electrophoresis, Gel, Pulsed-Field
- Escherichia coli
- Exotoxins
- Gene Expression Regulation, Bacterial
- Genes, Bacterial
- Genes, Regulator
- Molecular Sequence Data
- Mutation
- Pseudomonas aeruginosa
- Restriction Mapping
- Sequence Homology, Amino Acid