Human ubiquitin-activating enzyme (E1): compensation for heat-labile mouse E1 and its gene localization on the X chromosome.

doi:10.1016/0014-4827(91)90164-p

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Article

Human ubiquitin-activating enzyme (E1): compensation for heat-labile mouse E1 and its gene localization on the X chromosome.

Experimental cell research - 1 Jan 1991

Kudo M, Sugasawa K, Hori T, Enomoto T, Hanaoka F, Ui M

Abstract excerpt

We have constructed interspecific somatic cell hybrids between a temperature-sensitive (ts) mutant cell line of mouse FM3A cells, ts85, that has a heat-labile ubiquitin-activating enzyme (E1) and a human diploid fibroblast cell line, IMR-90. A hybrid clone that could grow stably at a nonpermissiv...

Topics

Animals
Chromosome Mapping
Clone Cells
Cloning, Molecular
Genetic Complementation Test
Histones
Humans
Hybrid Cells
Karyotyping
Ligases
Mice
Mutation
Temperature
Ubiquitin-Activating Enzymes
Ubiquitin-Protein Ligases
Ubiquitins
X Chromosome

Source

Open in PubMed

Identifiers

PMID: 1845793
DOI: 10.1016/0014-4827(91)90164-p

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1845793-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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