Article
Cloning and sequence of a functionally active cDNA encoding the mouse ubiquitin-activating enzyme E1.
Gene - 10 Sept 1992
Imai N, Kaneda S, Nagai Y, Seno T, Ayusawa D, Hanaoka F, Yamao F
Abstract excerpt
A cDNA encoding the ubiquitin-activating enzyme, E1, was isolated from the mouse mammary carcinoma cell line, FM3A, and shown to complement mutant mouse cells deficient in the enzyme. The 3495-bp cDNA encodes 1058 amino acids (aa), and shares extensive homology with the human E1 enzyme at both the nucleotide and aa sequence levels.
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