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Article

On combining family and case-control studies.

Genetic epidemiology - 1 Nov 2008

Pfeiffer Ruth M, Pee David, Landi Maria T

Abstract excerpt

Studies to detect genetic association with disease can be family-based, often using families with multiple affected members, or population based, as in population-based case-control studies. If data on both study types are available from the same population, it is useful to combine them to improve power to detect genetic associations. Two aspects of the data need to be accommodated, the sampling scheme and...

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PMID: 18454494
DOI: 10.1002/gepi.20338
PMCID: PMC8336588

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