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Article

The secreted metalloprotease ADAMTS20 is required for melanoblast survival.

PLoS genetics - 29 Feb 2008

Silver Debra L, Hou Ling, Somerville Robert, Young Mary E, Apte Suneel S, Pavan William J

Abstract excerpt

ADAMTS20 (Adisintegrin-like and metalloprotease domain with thrombospondin type-1 motifs) is a member of a family of secreted metalloproteases that can process a variety of extracellular matrix (ECM) components and secreted molecules. Adamts20 mutations in belted (bt) mice cause white spotting of the dorsal and ventral torso, indicative of defective neural crest (NC)-derived melanoblast development. The...

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Source

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Identifiers

PMID: 18454205
DOI: 10.1371/journal.pgen.1000003
PMCID: PMC2265537

Genes

ADAMTS20

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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The secreted metalloprotease ADAMTS20 is required for melanoblast survival.PMID 18454205Read ↗

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Emerging roles for ADAMTS5 during development and disease.Semantic proximity Read ↗

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