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Article

Specific haplotypes of the P-selectin gene are associated with myocardial infarction.

Human molecular genetics - 15 Aug 2002

Tregouet David-Alexandre, Barbaux Sandrine, Escolano Sylvie, Tahri Nadia, Golmard Jean-Louis, Tiret Laurence, Cambien François

Abstract excerpt

P-selectin is a cellular adhesion molecule that may be involved in the development of atherosclerosis and its complications. We have previously identified thirteen polymorphisms of the P-selectin gene among which five were located in the coding region of the gene (S290N, N562D, V599L, T715P, T741T (A/G)). These polymorphisms were tested individually for association with myocardial infarction (MI) and only the...

Topics

Adult
Case-Control Studies
Gene Frequency
Genetic Predisposition to Disease
Haplotypes
Humans
Linkage Disequilibrium
Middle Aged
Myocardial Infarction
P-Selectin
Polymorphism, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Promoter Regions, Genetic

Source

Identifiers

PMID: 12165563
DOI: 10.1093/hmg/11.17.2015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-12165563-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Specific haplotypes of the P-selectin gene are associated with myocardial infarction.PMID 12165563Read ↗

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