Article
The contribution of immune regulatory and thyroid specific genes to the etiology of Graves' and Hashimoto's diseases.
Autoimmunity - 1 Jan 2000
Ban Yoshiyuki, Tomer Yaron
Abstract excerpt
The autoimmune thyroid diseases (AITD) are complex diseases which are caused by an interaction between susceptibility genes and environmental triggers. Genetic susceptibility in combination with external factors (e.g. dietary iodine) are believed to initiate the autoimmune response to thyroid antigens. Abundant epidemiological data, including family and twin studies, point to a strong genetic influence on the...
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