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Article

Cancer risks from germ line tumor suppressor gene mutations.

Princess Takamatsu symposia - 1 Jan 1991

Frebourg T, Malkin D, Friend S

Abstract excerpt

It has been well established that sometimes cancer clusters within specific families. This has suggested the possibility that some of those families might carry genetic defects which provide susceptibility to specific cancers. Retinoblastoma, an embryonal tumor of the eye represents an extreme example of a tumor which has a dramatic genetic component. Several studies have shown that inactivation at the...

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PMID: 1844252

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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