Cancer risks from germ line tumor suppressor gene mutations.

Article

Cancer risks from germ line tumor suppressor gene mutations.

Princess Takamatsu symposia - 1 Jan 1991

Frebourg T, Malkin D, Friend S

Abstract excerpt

It has been well established that sometimes cancer clusters within specific families. This has suggested the possibility that some of those families might carry genetic defects which provide susceptibility to specific cancers. Retinoblastoma, an embryonal tumor of the eye represents an extreme ex...

Topics

Disease Susceptibility
Female
Genes, Retinoblastoma
Genes, p53
Humans
Li-Fraumeni Syndrome
Male
Mutation
Neoplasms
Risk

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