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Article

Molecular characterization of senescence marker protein-30 gene promoter: identification of repressor elements and functional nuclear factor binding sites.

BMC molecular biology - 29 Apr 2008

Rath Bandita, Pandey Ravi S, Debata Priya R, Maruyama Naoki, Supakar Prakash C

Abstract excerpt

BACKGROUND: Senescence marker protein-30 (SMP30), whose expression declines during aging in rat liver, has been proposed as an important aging marker. Besides apoptosis, SMP30 also protects cells against various other injuries by enhancement of membrane calcium-pump activity. The mechanism of this differential gene expression mechanism is not known. DNA-protein interactions, mutation analysis and luciferase...

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Identifiers

PMID: 18442420
DOI: 10.1186/1471-2199-9-43
PMCID: PMC2386801

Genes

SRY
GATA2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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