Article
Characterization of the Promoter Region of the Mouse Gene Encoding the Steroidogenic Acute Regulatory Protein
1 Feb 1997
Abstract excerpt
Steroidogenic acute regulatory protein (StAR) delivers cholesterol to the inner mitochondrial membrane, where the cholesterol side-chain cleavage enzyme carries out the first committed step in steroid hormone biosynthesis. StAR expression is restricted to steroidogenic cells and is rapidly induced by treatment with trophic hormones or cAMP. We analyzed the 5'-flanking region of the mouse StAR gene to elucidate...
