Article
The restricted expression pattern of the Hodgkin's lymphoma-associated cytokine receptor CD30 is regulated by a minimal promoter.
The Journal of pathology - 1 Oct 2000
Dürkop H, Oberbarnscheidt M, Latza U, Bulfone-Paus S, Hirsch B, Pohl T, Krause H, Hummel M, Stein H
Abstract excerpt
One of the most peculiar immunohistological characteristics of the tumour cells of Hodgkin's lymphoma, anaplastic large cell lymphoma (ALCL), and embryonal carcinoma of the testis is the expression of the CD30 antigen. Physiologically, CD30 expression is restricted to a few activated lymphocytes in normal lymphoid tissue and a small population of decidual cells. To clarify the reasons behind this highly...
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