Article
Claudin-16 reduces the aggressive behavior of human breast cancer cells.
Journal of cellular biochemistry - 1 Sept 2008
Martin Tracey A, Harrison Gregory M, Watkins Gareth, Jiang Wen G
Abstract excerpt
Claudin-16 (Paracellin-1) is a transmembrane tight junction (TJ) protein originally described as having a critical role in the re-absorption of magnesium and calcium in the kidney. This study examined expression of Claudin-16 in human breast cells and tissues to identify a possible link between expression and aggressiveness in cells and between Claudin-16 levels and patient prognosis. Insertion of the Claudin-16...
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