Article
[Genetic risk factors in autoimmune diabetes mellitus, their significance and function].
Casopis lekaru ceskych - 1 Jan 2004
Novota P, Cejková P, Cerná M, Andĕl M
Abstract excerpt
Autoimmune diabetes mellitus is characterized by selective destruction of beta pancreatic cells and by cellular infiltration with T- (particularly Th1) and B-lymphocytes. The marker of autoimmunity is the presence of autoantibodies (ICA, IAA, GADab, IA2ab). Etiology of the autoimmune process is still unknown. It is suggested that the pathogenesis is activated by genetic and environmental factors. Individual...
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