Article
[Immune markers of type-I diabetes mellitus in children with diabetes in their first-degree relatives. Part I].
Przeglad lekarski - 1 Jan 2003
Buczkowska Ewa Otto, Chobot Przemysława Jarosz
Abstract excerpt
Type 1 diabetes is the consequence of an autoimmune destruction of the pancreatic beta cells. During its progression such autoantibodies as ICA, anti-GAD, anti-IA2 and IAA are found. The disease develops in genetically predisposed individuals, the genetic predisposition is associated with HLA genes. The presence of autoantibody markers at diagnosis could help predict the rapid decrease in residual beta-cell...
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