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Article

Biomarkers of Inflammation and MRI-Defined Small Vessel Disease of the Brain: The Cardiovascular Health Study.

Stroke - 1 Jul 2008

Fornage Myriam, Chiang Y Aron, O'Meara Ellen S, Psaty Bruce M, Reiner Alexander P, Siscovick David S, Tracy Russell P, Longstreth W T

Abstract excerpt

BACKGROUND AND PURPOSE: To clarify the role of inflammation in the pathogenesis of small vessel disease of the brain, we investigated the association between common variation in the C-reactive protein (CRP) and interleukin (IL)-6 genes, plasma CRP and IL6 levels, and presence of MRI-defined white matter lesions (WML) and brain infarcts (BI) in elderly participants of the Cardiovascular Health Study. METHODS: Tag...

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Identifiers

PMID: 18436879
DOI: 10.1161/STROKEAHA.107.508135
PMCID: PMC2888487

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CRP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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