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Article

Functional interaction of regulatory factors with the <i>Pgc-1</i> α promoter in response to exercise by in vivo imaging

23 Apr 2008

Abstract excerpt

Real-time optical bioluminescence imaging is a powerful tool for studies of gene regulation in living animals. To elucidate exercise-induced signaling/transcriptional control of the peroxisome proliferator-activated receptor-gamma coactivator-1alpha (Pgc-1alpha) gene in skeletal muscle, we combined this technology with electric pulse-mediated gene transfer to cotransfect the Pgc-1alpha reporter gene with plasmid...

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PMID: 18434626
DOI: 10.1152/ajpcell.00104.2008

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