Article
RAB-10 regulates glutamate receptor recycling in a cholesterol-dependent endocytosis pathway.
Molecular biology of the cell - 1 Nov 2007
Glodowski Doreen R, Chen Carlos Chih-Hsiung, Schaefer Henry, Grant Barth D, Rongo Christopher
Abstract excerpt
Regulated endocytosis of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-type glutamate receptors (AMPARs) is critical for synaptic plasticity. However, the specific combination of clathrin-dependent and -independent mechanisms that mediate AMPAR trafficking in vivo have not been fully characterized. Here, we examine the trafficking of the AMPAR subunit GLR-1 in Caenorhabditis elegans. GLR-1 is localized...
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