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Article

Consequences of the disease-related L78R mutation for dimerization and activity of STAT3.

Journal of cell science - 1 May 2014

Domoszlai Tamás, Martincuks Antons, Fahrenkamp Dirk, Schmitz-Van de Leur Hildegard, Küster Andrea, Müller-Newen Gerhard

Abstract excerpt

Signal transducer and activator of transcription 3 (STAT3) is a transcription factor that is centrally involved in diverse processes including haematopoiesis, immunity and cancer progression. In response to cytokine stimulation, STAT3 is activated through phosphorylation of a single tyrosine resi...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24569879
DOI: 10.1242/jcs.137422

Genes

STAT3
STAT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24569879-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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