Article
Effects of interacting networks of cardiovascular risk genes on the risk of type 2 diabetes mellitus (the CODAM study).
BMC medical genetics - 24 Apr 2008
van Greevenbroek Marleen M J, Zhang Jian, Kallen Carla J H van der, Schiffers Paul M H, Feskens Edith J M, de Bruin Tjerk W A
Abstract excerpt
BACKGROUND: Genetic dissection of complex diseases requires innovative approaches for identification of disease-predisposing genes. A well-known example of a human complex disease with a strong genetic component is Type 2 Diabetes Mellitus (T2DM). METHODS: We genotyped normal-glucose-tolerant subjects (NGT; n = 54), subjects with an impaired glucose metabolism (IGM; n = 111) and T2DM (n = 142) subjects, in an...
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