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Article

Adaptive plasmid evolution results in host-range expansion of a broad-host-range plasmid.

Genetics - 1 Apr 2008

De Gelder Leen, Williams Julia J, Ponciano José M, Sota Masahiro, Top Eva M

Abstract excerpt

Little is known about the range of hosts in which broad-host-range (BHR) plasmids can persist in the absence of selection for plasmid-encoded traits, and whether this "long-term host range" can evolve over time. Previously, the BHR multidrug resistance plasmid pB10 was shown to be highly unstable in Stenotrophomonas maltophilia P21 and Pseudomonas putida H2. To investigate whether this plasmid can adapt to such...

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Identifiers

PMID: 18430943
DOI: 10.1534/genetics.107.084475
PMCID: PMC2323807

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