Article

Within-patient evolution of plasmid-mediated antimicrobial resistance

2022-05-31

Abstract excerpt

Antibiotic resistance (AMR) in bacteria is a major threat to public health, and one of the key elements in the spread and evolution of AMR in clinical pathogens is the transfer of conjugative plasmids. The drivers of AMR evolution have been extensively studied in vitro , but the evolution of plasmid-mediated AMR in vivo remains poorly explored. Here, we tracked the evolution of the clinically-relevant plasmid pO...

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Literature Corpus work: 3c7a5fcb-819d-57ff-be88-9def364b47d5
DOI: 10.1101/2022.05.31.493991

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