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Knockout of the gene encoding the extracellular matrix protein <scp>SNED1</scp> results in early neonatal lethality and craniofacial malformations

4 Oct 2020

Abstract excerpt

BACKGROUND: The extracellular matrix (ECM) is a fundamental component of multicellular organisms that orchestrates developmental processes and controls cell and tissue organization. We previously identified the novel ECM protein SNED1 as a promoter of breast cancer metastasis and showed that its level of expression negatively correlated with breast cancer patient survival. Here, we sought to identify the roles of...

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PMID: 33012048
DOI: 10.1002/dvdy.258

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