Article
Tumor necrosis factor-alpha and interleukin-10 gene promoter polymorphisms in Turkish rheumatoid arthritis patients.
Clinical rheumatology - 1 Oct 2008
Ates Omer, Hatemi Gulen, Hamuryudan Vedat, Topal-Sarikaya Aysegul
Abstract excerpt
Tumor necrosis factor and interleukin 10 have been implicated in the pathogenesis of rheumatoid arthritis (RA). Certain single-nucleotide polymorphisms (SNPs) within the promoter region of the IL-10 and TNF genes have been associated with altered levels of circulating IL10 and TNF. We aimed to ex...
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