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Article

Association of polymorphisms in the human IL-10 and IL-18 genes with rheumatoid arthritis.

Molecular biology reports - 1 Jan 2011

Ying Binwu, Shi Yunying, Pan Xiaofu, Song Xingbo, Huang Zhunchun, Niu Qian, Cai Bei, Wang Lanlan

Abstract excerpt

The decrease of anti-inflammatory cytokine and increase of pro-inflammatory cytokine was observed in rheumatoid arthritis (RA). Interleukin-10 (IL-10), a potent anti-inflammatory cytokine, has been demonstrated to suppress joint swelling and deformation in RA animal model. Interleukin-18 (IL-18), a widely distributed pro-inflammatory cytokine, induces the production of IFN-γ, activate NK cells, and promote...

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PMID: 20424918
DOI: 10.1007/s11033-010-0119-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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