Article
Interleukin-10 gene promoter polymorphism in Polish rheumatoid arthritis patients.
International journal of immunogenetics - 1 Aug 2010
Paradowska-Gorycka A, Trefler J, Maciejewska-Stelmach J, Łacki J K
Abstract excerpt
Interleukin (IL)-10 is an important multifunctional cytokine with both anti-inflammatory and immunoregulatory effects in rheumatoid arthritis (RA). In the present study, we evaluated the frequency and potential impact of IL-10 promoter polymorphisms on susceptibility to and severity of RA in Polish in - patients with a high disease activity (mean DAS 28 C-reactive protein 5.25). DNA was obtained from 244 RA...
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