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Article

Polymorphisms in CYP1B1, GSTM1, GSTT1 and GSTP1, and susceptibility to breast cancer.

Oncology reports - 1 May 2008

Van Emburgh Beth O, Hu Jennifer J, Levine Edward A, Mosley Libyadda J, Perrier Nancy D, Freimanis Rita I, Allen Glenn O, Rubin Peter, Sherrill Gary B, Shaw Cindy S, Carey Lisa A, Sawyer Lynda R, Miller Mark Steven

Abstract excerpt

Polymorphisms in the cytochrome P450 1B1 (CYP1B1) and glutathione S-transferase (GST) drug metabolic enzymes, which are responsible for metabolic activation/detoxification of estrogen and environmental carcinogens, were analyzed for their association with breast cancer risk in 541 cases and 635 controls from a North Carolina population. Each polymorphism, altering the catalytic function of their respective...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP1B1

Share to Gene Expression Regulation, Neoplastic

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Share to Polymorphism, Genetic

Source

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Identifiers

PMID: 18425393
PMCID: PMC3668546

Genes

GSTP1
GSTT1
GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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