Article
Consistently replicating locus linked to migraine on 10q22-q23.
American journal of human genetics - 1 May 2008
Anttila Verneri, Nyholt Dale R, Kallela Mikko, Artto Ville, Vepsäläinen Salli, Jakkula Eveliina, Wennerström Annika, Tikka-Kleemola Päivi, Kaunisto Mari A, Hämäläinen Eija, Widén Elisabeth, Terwilliger Joseph, Merikangas Kathleen, Montgomery Grant W, Martin Nicholas G, Daly Mark, Kaprio Jaakko, Peltonen Leena, Färkkilä Markus, Wessman Maija, Palotie Aarno
Abstract excerpt
Here, we present the results of two genome-wide scans in two diverse populations in which a consistent use of recently introduced migraine-phenotyping methods detects and replicates a locus on 10q22-q23, with an additional independent replication. No genetic variants have been convincingly established in migraine, and although several loci have been reported, none of them has been consistently replicated. We...
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