Article
A novel locus for familial migraine on Xp22.
Headache - 1 Jun 2010
Wieser Thomas, Pascual Julio, Oterino Agusto, Soso Michael, Barmada Michael, Gardner Kathy L
Abstract excerpt
INTRODUCTION: Migraine is thought to be genetically complex. There is evidence of an X-linked dominant genetic component. A locus at Xq24-q28 has already been described supporting this hypothesis. METHODS: The X chromosome in 61 migraine families was screened using markers spanning the entire chromosome. Alleles were assigned using the GeneScan Analysis software, analysis for affected relative allele sharing and...
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